From the plaque:
In 1812 David Stuart, who had traversed this region the year before, built the first post here for the Astor's Pacific Fur Company. The North West Company, which also built here in 1812, bought out the Astorians in 1813, and in 1821 the post passed to the Hudson's Bay Company. Although it was Commercially insignificant, Kamloops was important because it lay astride the brigade route from the Columbia Department to New Caledonia and because its rich grasslands enebled the company to raise packhorses here. As provincial roads improved the post became superfluous, and 1885 had been abandoned.
Although Kamloops had a short life as a fort, the city has become a modern centre for transportation.
Wikipedia has a pretty comprehensive page on Kamloops including it's history and can be found here.
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